Researchers of the human gut microbiome have made connections to the autism spectrum disorder. A gut microbiome involves the digestive tract microbes. To learn more general information click here. Studies tested DNA of children with gastrointestinal complaints. Researches compared children with Autism Spectrum Disorder, and mainstream children. It was found that children with Autism Spectrum Disorder had too many Clostridium or Desulfovibrio clusters. To learn more about these gene clusters click here. Developing fever, receiving oral antibiotics, or ingesting probiotics are all likely to alter the gut microflora. When children with Autism Spectrum Disorder do the above, they have exhibited improvement in their gastrointestinal pains; however, there hasn’t been scientific research, as it has only been found anecdotally. Research has been limited due to the difficult culture-dependent techniques; however, metagenomic technology could be used to discover and reduce the effects of the gut microbiome as a part in Autism Spectrum Disorder.
A longitudinal study completed in May 2016 shows more progress that scientists have made in discovering different aspects of autism in relation to the microbiome. For two weeks, stool samples were collected from patients with autism and their siblings without autism in order to be compared. Sarcina ventriculi, Barnesiella intestihominis, and Clostridium bartlettii are organisms that are related to autism. They were found in the stool samples of children with autism, but not their siblings. Gastrointestinal symptoms were reported on days 6-8 of the study for children with Autism Spectrum Disorder, where Haemophilus parainfluenzae was detected at the onset. These patients also exhibited behavioral challenges during these days.
Though scientists have not found a diagnosis for Autism Spectrum Disorder yet, it is clear that the gut microbiome plays a role in the development. Further research that is not merely based off of a handful of patients needs to be completed to learn more.
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