BioQuakes

AP Biology class blog for discussing current research in Biology

Tag: #Robots

Robot Pills And The Future Of How Medication Is Delivered

For years society has struggled to develop an efficient way to deliver complex drugs through the body. But this is not the case anymore; thanks to biomedical engineer Shriya Srinivasan we can take pills for medicines that we would not usually be able to. For example, Cancer drugs, Diabetes drugs, and many other drugs that require a shot. 

Smallpox vaccine

“say goodbye to painful shots”

According to Megan Rosen’s article, Shriya Srinivasan’s invention of the robot would be “a huge game changer” in the medical industry. Before her invention, pills struggled to enter the bloodstream because of the mucus that would trap the pill from entering the stomach acids so it could dissolve. However, with the Robot pill, we can overcome the mucus and enter the stomach, where the acid will dissolve, and the desired drug will enter the bloodstream.

Robot pill in action video link

The robot pills use unique engineering methods to break up the mucus in a path. Some of these methods consist of surface grooves and small torpedo fins to break up the mucus in the human body. But, there is only one problem; breaking up mucus is a difficult task. This is because mucus has proteins, specifically glycoproteins, bonded strongly by covalent bonds. Covalent bonds are the strongest because they share an even amount of electrons. The strong covalent bonds make it difficult to break up the substance, which is where the fin and surface grooves come to break up the bonds of the strong mucus proteins.

Human alfa2beta2 hemoglobin

With new inventions, people save lots of time and pain. Society will no longer have to inject shots into the body but rather take a pill. That said, we ultimately conclude that robotic pills are the future of medicine.

 

Robot Frogs??

Yes, you read that title right. A team at the University of Vermont has figured out how to make robot frogs. These life forms are only millimeters long and are neither a living organism or robot. Currently, they can move toward a target and heal themselves after being injured, but not much else. One of their creators, Joshua Bongard, referred to them as “Novel living machines” and also said, “They’re neither a traditional robot nor a known species of animal. It’s a new class of artifact: a living, programmable organism.” The new creature was designed on a supercomputer at the University of Vermont, but was actually assembled and tested by biologists at Tufts University.

The creators of this new form of life see many different opportunities for it to do good, like searching out radiation, or gathering microplastics from the oceans, or even clearing plaque from arteries. Genetically engineering organisms has always been a widespread thing, but this is the first ever time that something was genetically modified from the ground up. The supercomputer at the University of Vermont ran hundreds of algorithms to test the optimal design for the organism, it would take many types of cells and put them into a bunch of forms and body shapes. Until they were finally able to decide on the optimal body type, thanks to the help of this computer. After the shape was decided the scientists at Tufts then incubated each cell on its own then used tiny forceps and an electrode in order to merge the cells together. They were then assembled into a form never seen before in nature, they were able to move in coherent fashion, but struggled from getting up from their backs like a beetle or a newborn baby.

Personally, I think the biggest use for this technology is drug delivery throughout the body. Certain medicines for certain diseases that only affect a certain region of the body need to be delivered directly to the source, and taking it orally, or even through injection cannot get it there with the effectiveness that something like a frog carrying a certain treatment like a mailman could, which could mean a lot for medicine. These robots would also be the perfect messengers because they can rapidly heal themselves, since they are comprised of stem cells, if they were to be attacked by the immune system, and because after 7 days they can be programmed to stop working and become regular dead skin cells. So, in turn, they are both biodegradable and effective. Robot frogs are cool, but there is also a lot of uses for them, and a lot of ways this silly invention can help the world.

 

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