BioQuakes

AP Biology class blog for discussing current research in Biology

Tag: Milk

A “Coffee-With-Milk” A Day Keeps The Doctor Away

In a recent study, researchers at the Department of Food Science, in collaboration with researchers from the Department of Veterinary and Animal Sciences, at the University of Copenhagen have discovered evidence that the mixture of coffee and milk has anti-inflammatory effects when consumed.

On January 30th, a study was published in the Journal of Agricultural and Food Chemistry (led by Professor Marianne Nissen Lund) that explains how this common combination of ingredients can limit inflammation.  To test the theory, the study “applied artificial inflammation to immune cells.  Some cells received various doses of polyphenols that had reacted with an amino acid, while others only received the same doses. A control group received nothing” (Science Daily).

The results showed that cells that received a dosage of polyphenols and amino acids were twice as effective as cells that received purely polyphenols.  Now, you may be asking how this relates to coffee and milk?  The answer to this question lies in the definitions of terms used above.  Polyphenols are a “category of plant compounds that offer health benefits” (Healthline).  They are found in coffee beans, and therefore, coffee.  Amino acids are “molecules that combine to form proteins,” and therefore are found in a majority of animal products, including milk (Medline Plus).

It is an established fact in the scientific community that polyphenols and amino acids bond, and therefore, the link between the two substances and anti-inflammatory effects is believable to scientists after the recent study performed by the Department of Food Science.  Furthermore, considering how common both substances are, it is likely that a similar reaction occurs when protein is combined with other fruits and vegetables with high amounts of polyphenol.  According to Marianne Nissen Lund, “I can imagine that something similar happens in, for example, a meat dish with vegetables or a smoothie, if you make sure to add some protein like milk or yogurt”.

The immune system is incredibly important to the function of the human body, as it serves to maintain order and defend against both foreign and local threats. When pathogens are able to infiltrate the body, they trigger innate immunity defenses, which in turn causes inflammation (as histamines which are released dilate local blood vessels and increase capillary permeability and cause the area to swell with fluid, which thus, causes inflammation).

Although immune cells (and in particular, innate immunity) cause inflammation, it is also the job of the immune system to limit inflammation by fighting off any unwanted antigen quickly, as the faster the antigen is killed, the faster inflammation goes away.  Immune cells of all types serve this function, ranging from innate to adaptive.  Thus, a compound that can increase the reaction rate of immune cells is incredibly valuable to animal health, including human health.

The results of the study show that polyphenols that have reacted with amino acids can double the effectiveness of the anti-inflammatory process of immune cells.  So, next time you are ordering a coffee, remember to ask for a splash of milk – you just might thank me later.

Coffee with milk (563800) (cropped)

https://www.flickr.com/photos/usdagov/30884756422

If You Want the Bull, Take its Horns

Everyone loves milk. It’s the foundation of Ice Cream, it’s an essential component in any good bowl of cereal, it’s the foundational ingredient in the creamy center that unites the Oreo, and pro tip: you can put chocolate syrup in it (I thought of that; I call it “ChocoLeche” I think it could really catch on).

 

Before I continue, I’d like to take a moment of silence for those cursed by the demon known commonly as lactose intolerance. Your lives are a miserable nightmare that I don’t even want to think about. #findacure .

 

Like I said everyone loves milk, and everyone knows it comes from cows. Few people however are aware of the fact that the cow that produces milk is different than the cow that produces the much beloved meat products such as steak and hamburgers. The Cows that are used for meat are of the Angus variety. The Cows for dairy products are Holstein Cows. One major difference that used to exist between the two is that Holstein, or dairy cows, had horns, unlike the meatier Angus cows which did not have horns. Thanks to Crispr-Cas9, scientists from UC Davis lead by Dr. Alison Van Eenennaam have rid Holstein cows of their horns, and in doing so have granted dairy cows everywhere with a higher quality of life.

https://www.flickr.com/photos/usdagov/30884756422

Source

Photo by

U.S. Department of Agriculture

The first question that needs to be answered is why would this be important. Why does it matter that we got the horns off of Holsteins? It’s important first because these horns put cows at risk from each other. Cows with horns might advertently or inadvertently use them to injure themselves, other cows or their handlers. Many previously solved this problem by dehorning the cows, which involves burning the horns off and is extremely painful for the cows. Without horns to begin with no cows need to be dehorned and fewer cows are injured. As Dr. Jeff Burkhardt puts it “From the animal welfare perspective, Dr. Alison Van Eenennaam’s research is worthy of high praise: The prospect of reducing the pain associated with de-horning, which itself was introduced to eliminate risks of animals hurting themselves and others, is exactly the kind of thing that animal scientists should be doing” – Jeff Burkhardt. The Ethics of Gene editing in general is a complex and hotly debated issue right now due to the novelty of the CRISPR system, however, in this instance I feel as though the researchers are on very sound moral ground. They have made a change that safely and indisputably decreases the pain a dairy cow experiences. If you disagree I’d invite you to burn two holes in the side of your head, and reconsider whether you’re comfortable bestowing that treatment on another living creature.

The second question is how did they do this. The answer is deceptively simple. As I formerly noted, Angus cows do not possess horns. What they do possess is a gene that prevents the growth of a horn. The group of researchers at UC Davis first identified this gene and its cause. They then used CRISPR-Cas9 to cut it out of an Angus Cow’s DNA and inserted it into the DNA of a Holstein cow. The Angus cow gene prevents horn growth in Holstein cows, and the Holstein cows officially became a GMO, or genetically modified organism. A GMO that no longer has horns.

 

More Bacteria than Human?

The well being of humans is best when we are cooperating with others whether that be other humans or bacteria inside of us. According to Matthew Bull “the human gut microbiome and its role in both health and disease has been the subject of extensive research, establishing its involvement in human metabolism, nutrition, physiology, and immune function.” An imbalance in our microbiome will often result in some type of sickness so it is very important to keep our guts healthy. It is likely that there are more bacteria cells in our gut than there are our own cells. So in this image right here  there would be more bacteria cells than human cells. Some people even consider the microbiome a bacteria ecosystem that just happens to be in our gut. While this may sound bad, these bacteria often break down food for us and supply us with energy needed to do daily activities. It is truly fascinating to think that we have many living things inside of us that may even outnumber what is actually considered “us”. But is it possible for these bacteria to take over our bodies? The answer is probably no…we hope, but if we continue to eat well and stay healthy these bacteria should continue to help us. However, if we eat poorly and don’t stay healthy these bacteria can end up being a problem for use. So at the end of the day eating health helps the relationship between us and the bacteria inside of us stay healthy and lets us stay healthy.

The diet that we should have to keep a healthy relationship with these bacteria involve eating less sugar and fat and eating more fiber. A diet with a lot of fat and sugar but little fiber can lead to illness. It is also best to stay away from eating a lot of iron. There are some things that help our microbiomes such as milk, milk has proteins in it that help keep our microbiomes health. So eat less sugar, bad fats, and iron and eat more fiber and drink more milk.

 

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