dysbiosis – BioQuakes

The article, Gut microbiota’s effect on mental health: The gut-brain axis, touches upon the way in which the gut microbiome is connected to your central nervous system and how they affect each other. It explains how the vagus nerve and afferent fibers connect your gut to your brain and helps control your mood by indirectly affecting the amount of Serotonin in your brain. An unhealthy microbiome or dysbiosis is correlated with a large number mental illnesses such as depression, anxiety, schizophrenia and bipolar disorder. It also mentions that the gut microbiome may also be able to affect your immune and endocrine system as well the central nervous system. The article concludes that the improvement of peoples gut microbiota may serve as an effective treatment for those with a number of mental disorders through the means of probiotics. The article Feeling Meh? This is How Your Gut Affects Your Mood(Plus, Exactly How to Fix It) goes through an example of a man who dealt with serious depression and had tried antidepressants and felt only more unhappy while on them. He decided to change his diet instead to one high in vegetables and fiber as well as healthy amounts of protein and fat. The man felt he had more energy, he felt much less anxious and depressed and even felt he gained a much stronger sense of empathy which improved his relationships only furthering his happiness. Do you want to be Happier? Healthier? Have a stronger immune system? Well then you better eat your probiotics and prebiotics. If you want to do some more research yourself check out this article: Article 2

The gut microbiome is a very large collection of mutualistic relationships between microorganisms and an animal. In our case, these microorganisms control very much of the digestive tract and have influences throughout the body. Crohn’s disease is something that can happen due to imbalance in this microbiome or “dysbiosis“. Usually marked by inflammation in the digestive tract, this disease is a result of an autoimmune response against possibly microbial antigens. Although there is no cure, scientists have determined the best course of action is to relieve the symptoms. This results in disruptions to the gut microbiome.

Inflammation of the colon due to Crohn’s disease

Scientists studying responses in the gut microbiome have found that treatment for Crohn’s disease have caused various responses in the people in the experiment. Antibiotics have been found to decrease bacterial growth in the tract while allowing fungus to grow more freely. Formula diets relieved inflammation and other symptoms but didn’t repair bacterial balance in the microbiome. Immunosuppressants decreased inflammation and bacterial dysbiosis at the expense of increasing fungal dysbiosis. All these methods don’t seem to work out.

But what if the microbiome does not need to be restored to remain healthy? Formula diets caused more dysbiosis but were able to alleviate symptoms. Suddenly, the microbiome does not seem to be as necessary as previous studies suggest. However, this experiment only measures a few variables. Results beneficial to treatments for Crohn’s disease may cause something bad to happen elsewhere in the microbiome. Replacing the gut microbiome would definitely have massive side effects.

Perhaps one day, we could find some way to substitute parts of our mutualistic relationship with the bacteria inhabiting our gut. However, that day seems far off. For now, we should probably stick with what we have.

Original Article

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Tag: dysbiosis

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