Researchers University of Tokyo Department of Applied Biological Chemistry have found evidence that the time of day may influence one’s forgetfulness. They were able to study this by identifying and studying a gene in mice that controls memory.
The key to their research was making a test that differentiates between never learning information versus not remembering information. To ensure that the mice learned new information, the mice were given a new object and then given the same object later in the day. The mice were considered to have “learned” new information if they spent less time exploring the new object.
Researchers repeated this experiment with mice that had BMAL1 and with mice that did not have BMAL1. BMAL1 is a protein that controls different genes and normally fluctuates between high and low levels. Through tests, researchers discovered that the mice without the BMAL1 (normal mice), were more forgetful when they first woke up.
Though the researcher’s findings may indicate that humans are also more forgetful early in the morning, more research meeds to be done. Scientists are currently trying to find ways to strengthen memory through the BMAL1 pathway, that can possibly help cure diseases such as Alzheimer’s and dementia. They are also curious to determine the evolutionary benefit of having less memory ability later in the day. This study can be seen as the first step towards a major scientific discovery.