New York State just placed the first temporary ban on the distribution of flavored e-cigarettes. Although this motion was repealed last week due to the “state’s executive overreach” (Tony Abound of Vapor Technology Association), the ban will be rediscussed on October 18th. Actions to reduce use of e-cigarettes are gaining momentum. This is in part due to a recent article discussing a study involving mice, which linked e-cigarette smoke to lung adenocarcinoma and bladder urothelial hyperplasia.
Just published two days ago, Moon-shong Tang, PhD of NYU School of Medicine, studied the affect of e-cigarette smoke on forty mice. Over a 54 week period of exposure, the results were both shocking and devastating. Twenty-three of the forty mice (57.5%) developed bladder urothelial hyperplasia (lack of cytologic atypia in thickened urothelium), changes in gene multiplication, and cancerous abnormal tissue growth. In addition, nine of the mice (22.5%) developed lung adenocarcinomas, a divison of lung cancer. Although the study was restricted due to the small trial size and the full-body smoke exposure opposed to inhalation, it is still prevalent to consider this trail in the dangers of e-cigarettes.
Once nicotine enters a cell, nitrosation (addition of a nitrosonium ion) converts nicotine to nitrosamines, a proven carcinogen. Although a 2017 study revealed nitrosamines in e-cigarette smokers was 95% less than in tobacco smokers, a new study proves mammalian cells already contain nitrosonium which react with inhaled nicotine to produce nitrosamines. Nitrosamine is unable to leave the cell, and therefore is undetectable by blood tests.
E-cigarettes have infiltrated todays society, specifically affecting teenagers and young adults. With appealing flavors and attractive packaging, e-cigarettes has swayed away from helping recovering smokers, to targeting young individuals, who generally have never smoked a cigarette before. I was not surprised to hear this trial’s results, as teenagers across the country have been experiencing hospitalization due to collapsed lungs and other illnesses related to e-cigarettes. I urge everyone to consider the consequences of e-cigarettes before using one.
For more details involving the trail, click here.