Yep, that’s right. Poop can be valuable.
Wait? Isn’t that an oxymoron? Valuable poop?
Yes, as much of an oxymoron as it sounds, poop can be valuable. In a more recent treatment, fecal transplants have proved to be successful in helping with C. difficile infections. Antibiotics stop working, and all hope seems lost. However, there is a solution. Healthy people donate their stool (in the vernacular: poop) to those afflicted by a C. difficile infection in order to restore the health of their gut microbiome. The healthy microbial environment in the healthy stool restores the balance.
How does this work? Do the microbiomes go to war?
Truth is, researchers are still trying to figure out exactly how the healthy gut microbiome is restored. We know that C. difficile can take over after treatment with antibiotics because it is faster growing and more resistant to antibiotics. They dominate the other microbes. The insertion of healthy stool with a balanced microbiome into a microbiome that is dominated by C. difficile will restore the microbiome’s diversity and balance. Basically, the healthy gut microbiome will kill or just outnumber the C. difficile, and then the problem is resolved. Scientists still aren´t really sure how this happens but are looking into it.
So what? I’ve never heard of a C. Difficile infection?
Good for you. C. Difficile has actually been afflicting many people in different ways, and some doctors even call it an ‘epidemic’. Even so, this new development has lead researches to believe that this could lead to something bigger. Some have tested if this same technique will help inflammatory bowel disease, to which they had promising results (however, still heterogeneous and statistically inconclusive). This is a creative way of using the microbial environment to help diseases, and an even more creative way to study microbial interactions.
Would you get a fecal transplant if it were recommended?
How do you think the C. Difficile is banished by the other microbes?
What do you think regarding the future of antibiotics?