BioQuakes

AP Biology class blog for discussing current research in Biology

Tag: addicted

Why do only some COCAINE users become addicted?

The obvious precursor to cocaine addiction is cocaine use. However, some people are able to use cocaine on and off with out becoming addicted while others become afflicted by addiction very quickly. There has always been the theory that your personality can make you more prone to addictions and other “weak” decisions but recent studies go a step beyond that and link addiction to the structure of an individual’s brain.

The frontal lobe of the brain is associated with self-control. The size of the frontal lobe appears to indicate how susceptible an individual would be to cocaine addictions. A study done by scientists at the University of Cambridge compared the brains of casual cocaine users versus cocaine addicts. What they found was a noticeable difference in size of the frontal lobe: users had a larger frontal lobe while addicts had a smaller frontal lobe.

The scientists believe that the size difference was preexistent and  not a result of drug use because both groups were cocaine users. The main difference was that the mere users “could take it or leave it” due to their more powerful self control.

The brain is a popular subject when it comes to addictions due to the harm addictions can cause and due to the hope of a better understanding of addictions so that they can be “cured”. There are newly defined addictions more and more frequently, as addictions to food, caffeine, internet, and shopping become more and more prevalent.

Another example of increased susceptibility to addiction is the genetic or hereditary quality of alcoholism. “Though the exact mechanisms haven’t been identified, experts in alcoholism widely agree that some people are genetically vulnerable to developing the disorder.” Also, experts suggest that many people addicted opiates may have “deficiencies in their brain reward systems.”

Further studies exploring the links to the brain and addictions would be instrumental in curing the countless addictions that interfere with people’s quality of life.

 

Link to Main Article: http://www.nytimes.com/2013/02/05/science/brain-shape-may-play-role-in-cocaine-addiction.html?ref=science&_r=0

Link to additional articles:

http://www.nbcnews.com/id/3076712/#.URBDX81RLzc http://www.time.com/time/interactive/0,31813,1640235,00.html

Link to the photo used:http://www.flickr.com/photos/nationalarchives/4327205241/

 

 

Mothers: Avoid Drugs for Pain so Your Baby is Sane

photo cred: localtvkstu.files.wordpress.com

While pregnant or in labor, women experience amounts of pain that most men couldn’t dream of. They have to put up with this pain somehow…so according to a recent article, over the last decade, there has been a rise in use of prescription pain killers that has spread to maternity wards in the US. Unfortunately, because these painkillers are opiate-based, there has also been a rapid increase in the number of pregnant women addicted to opiates and also the number of babies born with withdrawal symptoms.

A study in the Journal of the American Medical Association has estimated that about one baby every hour is born with opiate withdrawal symptoms, and about 13,500 per year. According to the study, this condition, known as neonatal abstinence syndrome, results in seizures, breathing problems, dehydration, difficulty feeding, tremors and irritability in infants at birth. These infants must be hospitalized for up to many weeks while doctors ween them of their opium dependence with smaller doses of morphine or methadone.

The study, after looking at two databases consisting of “representative samples” from patients across the country, made two shocking discoveries. Over the period from 2000-2009, the number of pregnant women using opiate pain killers increased to five times as much, while the number of babies diagnosed with neonatal abstinence syndrome tripled at the same rate.

Not only is it an awful thing for these infants to be born addicted to opiates, but it also takes “a tremendous amount of nursing care” and time to cure these babies, according to Dr. Mark Hudak of the University of Florida College of Medicine. In the study, infants averaged about 16 days in the hospital. It takes them this long to be initially “cuddled,” placed in a dark room, then given tapered doses of methadone or morphine until the baby is weened. However, Hudak also states that “[morphine and methadone] are easy to overdose babies with” and that “there have been deaths” in this treatment.

According to the article, doctors agree that the best approach to deal with this problem is to cure women of their addictions before they are pregnant and prescribe them little or no opiate painkillers.

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