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Scientists at the University of Virginia recently conducted a study that suggests a connection between social behaviors and epigenetic markers. The study of these markers could predict the social dispositions of individuals and predict future social issues.

The gene for Oxytocin receptor (OXTR) has the ability to carry various amounts of DNA methylation tags. Those low in methyl tags have a greater ability to utilize oxytocin and therefore have a less amplified fear response. Those with many DNA methyl tags are shown to exhibit a more exaggerated fear response. More finitely, the amount of OXTR methylation affected the amount of brain activity in the amygdala, fusiform, and insula. These regions of the brain are directly correlated with face and emotional processing. To prove this, researchers conducted MRI scans on healthy participants while showing them pictures of angry and fearful faces.

The study not only proved the importance of studying the possible effects of epigenetic markers on susceptibility and resistance to disease, but it also shed a light on the possibility of brain disorders such as autism, anorexia, and depression being linked to DNA methyl tags at the oxytocin receptor.

Broadly, this study changes the way we look at how our environment and upbringing shapes our future susceptibility to illness and disorders. As scientific investigation into this topic continues and expands, we may be able to predict an individual’s reaction to social situations with the prick of a finger.

Article Source: http://www.genengnews.com/gen-news-highlights/fear-response-may-be-epigenetically-amplified-or-muted/81250914/

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